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Cajun Chicken Fettuccine

I combined two pasta sauces and added Cajun seasoning for kick in this quick- mix casserole. Using frozen onions and peppers speeds things up even more. Or try adding mushrooms or frozen peas. —Rebecca Reece, Henderson, Nevada
  • Total Time
    Prep: 25 min. Bake: 25 min.
  • Makes
    8 servings


  • 8 ounces uncooked fettuccine
  • 1 large sweet onion, halved and sliced
  • 1 medium green pepper, cut into 1/4-inch strips
  • 1 medium sweet red pepper, cut into 1/4-inch strips
  • 2 tablespoons olive oil
  • 2 cups cubed cooked chicken
  • 4 teaspoons Cajun seasoning
  • 1 teaspoon minced garlic
  • 1 jar (15 ounces) Alfredo sauce
  • 1/2 cup spaghetti sauce
  • 2 cups shredded part-skim mozzarella cheese
  • 1/2 cup grated Parmesan cheese


  • Cook fettuccine according to package directions. Meanwhile, in a large skillet, saute onion and peppers in oil until tender. Add the chicken, Cajun seasoning and garlic; heat through. Transfer to a large bowl. Drain fettuccine; add to chicken mixture. Stir in Alfredo and spaghetti sauces.
  • Transfer to a greased 13x9-in. baking dish. Sprinkle with cheeses. Cover and bake at 375° for 15 minutes. Uncover; bake 10-15 minutes longer or until golden brown.
Nutrition Facts
1 cup: 401 calories, 19g fat (9g saturated fat), 69mg cholesterol, 898mg sodium, 30g carbohydrate (5g sugars, 3g fiber), 27g protein.

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  • Lindsay
    Sep 5, 2020

    Very tasty and simple to make! My husband and son love it! This recipe has just enough spice to be good without being too hot.

  • cynandtom
    Mar 27, 2020

    I had high hopes for this one, and it did not disappoint. Fantastic!! Creamy, spicy, pasta goodness! The only change I made was chopping the onions and peppers, rather than slicing, and adding more garlic; just personal preference. Love this dish! Next time I’m going to double recipe so I can use a whole box of pasta, and have one to freeze.

  • wunsagin
    Sep 26, 2017

    Followed the recipe exactly and I was just overwhelmed with the salt from the cajun spice seasoning to the point that leftovers were tossed. I might make again but using a homemade seasoning minus the salt.

  • JoanieK53
    Mar 7, 2016

    Very Good. I roasted bone-in chicken breasts to get the 2 cups cooked chicken.

  • annrms
    Nov 7, 2015

    Awesome recipe! We really enjoyed the creamy tomato sauce with the "kick" of Cajun. I used whole what spaghetti instead. I also did not assemble it into a casserole; I served the delicious sauce over servings of pasta. Will definitely make this again.

  • AvidcookGAtoCA
    Nov 2, 2015

    You had me at "Cajun." We love spicy, so this caught my eye right away. My husband and I loved the creaminess of the sauce paired with the Cajun spice. Winner, Winner.

  • smagal
    Aug 11, 2015

    My husband loved it! and it was better than I thought since Cajun seasoning doesn't appeal to me.

  • fascinator
    Feb 28, 2015

    Delicious. Make again.

  • 4Huskers
    Aug 28, 2014

    I've made this twice now and we love it. It's so easy and totally delicious. Thanks for a great recipe!

  • TSimmons4579
    Jul 28, 2014

    T. Hanna, I completely agree. What's the point in pinning it, if someone just decides to take over with another recipe?!? I can't comment on this recipe but here's the link that this page used to take us to.'m having it for dinner tonight!